Publicaciones

  1. Ahmad R, Barcellini A, Baumann K, et al. Particle beam radiobiology status and challenges: a PTCOG Radiobiology Subcommittee report. International Journal of Particle Therapy. 2024, 100626, ISSN 2331-5180. doi:10.1016/j.ijpt.2024.100626
  2. Navarro R, Frago S, Hangiu O, et al. Pharmacokinetics and safety of LEAD-452, an EGFR-specific 4-1BB-agonistic trimerbody in non-human primates. Toxicology and Applied Pharmacology. 2024;487:116961. doi:10.1016/j.taap.2024.116961
  3. Magro N, Oteo M, Romero E, et al. Target engagement of an anti-MT1-MMP antibody for triple-negative breast cancer PET imaging and beta therapy. Nuclear Medicine and Biology. 2024;136-137:108930. doi:10.1016/j.nucmedbio.2024.108930
  4. González MI, González-Arjona M, Cussó L, et al. In Vivo Detection of Staphylococcus aureus Infections Using Radiolabeled Antibodies Specific for Bacterial Toxins. Bayford RH, ed. International Journal of Biomedical Imaging. 2024;2024:1-17. doi:10.1155/2024/3655327
  5. De Scals S, Fraile LM, Udías JM, et al. Feasibility study of a SiPM-fiber detector for non-invasive measurement of arterial input function for preclinical and clinical positron emission tomography. EJNMMI Phys. 2024;11(1):12. doi:10.1186/s40658-024-00618-2
  6. De Scals S, Fraile LM, Udías JM, et al. Correction: Feasibility study of a SiPM-fiber detector for non-invasive measurement of arterial input function for preclinical and clinical positron emission tomography. EJNMMI Phys. 2024;11(1):22. doi:10.1186/s40658-024-00624-4
  7. Passannante R, Gómez-Vallejo V, Sagartzazu-Aizpurua M, et al. Pharmacokinetic Evaluation of New Drugs Using a Multi-Labelling Approach and PET Imaging: Application to a Drug Candidate with Potential Application in Neuromuscular Disorders. Biomedicines. 2023;11(2):253. doi:10.3390/biomedicines11020253
  8. Orihuel J, Capellán R, Casquero-Veiga M, et al. The long-term effects of adolescent Δ9-tetrahydrocannabinol on brain structure and function assessed through neuroimaging techniques in male and female rats. European Neuropsychopharmacology. 2023;74:47-63. doi:10.1016/j.euroneuro.2023.05.005
  9. Ibáñez-Moragues M, Fernández-Barahona I, Santacruz R, et al. Zinc-Doped Iron Oxide Nanoparticles as a Proton-Activatable Agent for Dose Range Verification in Proton Therapy. Molecules. 2023;28(19):6874. doi:10.3390/molecules28196874
  10. Capellán R, Orihuel J, Marcos A, et al. Interaction between maternal immune activation and peripubertal stress in rats: impact on cocaine addiction-like behaviour, morphofunctional brain parameters and striatal transcriptome. Transl Psychiatry. 2023;13(1):84. doi:10.1038/s41398-023-02378-6
  11. Arce P, Lagares JI, Azcona JD, Huesa-Berral C, Burguete J. Precise dosimetric comparison between GAMOS and the collapsed cone convolution algorithm of 4D DOSE accumulated in lung SBRT treatments. Radiation Physics and Chemistry. 2023;208:110891. doi:10.1016/j.radphyschem.2023.110891
  12. Sanchez D, Gomez S, Mauricio J, et al. HRFlexToT: A High Dynamic Range ASIC for Time-of-Flight Positron Emission Tomography. IEEE Trans Radiat Plasma Med Sci. 2022;6(1):51-67. doi:10.1109/TRPMS.2021.3066426
  13. Mulero F, Oteo M, Garaulet G, et al. Development of anti-membrane type 1-matrix metalloproteinase nanobodies as immunoPET probes for triple negative breast cancer imaging. Front Med. 2022;9:1058455. doi:10.3389/fmed.2022.1058455
  14. Massó-Vallés D, Beaulieu ME, Jauset T, et al. MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding. Cancer Research Communications. 2022;2(2):110-130. doi:10.1158/2767-9764.CRC-21-0103
  15. Domingo C, Lagares JI, Romero-Expósito M, et al. Peripheral Organ Equivalent Dose Estimation Procedure in Proton Therapy. Front Oncol. 2022;12:882476. doi:10.3389/fonc.2022.882476
  16. Calvo Manuel FÁ, Serrano J, Solé C, et al. Clinical feasibility of combining intraoperative electron radiation therapy with minimally invasive surgery: a potential for electron-FLASH clinical development. Clin Transl Oncol. 2022;25(2):429-439. doi:10.1007/s12094-022-02955-z
  17. Calvo FA, Ayestaran A, Serrano J, et al. Practice-oriented solutions integrating intraoperative electron irradiation and personalized proton therapy for recurrent or unresectable cancers: Proof of concept and potential for dual FLASH effect. Front Oncol. 2022;12:1037262. doi:10.3389/fonc.2022.1037262

Congresos (Unidad de Aplicaciones Médicas de las Radiaciones Ionizantes)

  1. Aitor Herraiz, Juan Pellico, Unia Cossío, Eduardo Romero-Sanz, Rafael De Rosales Jesús Ruiz-Cabello, Miguel Ángel Morcillo-Alonso, Fernando Herranz. Iron oxide as general radionuclide chelator for multimodal imaging and therapy of cancer. EMIM2024 (12-15/03/2024; Porto, Portugal).
  2. Natalia Magro, Miguel Angel Morcillo, Lukas M Carter, Marta Oteo, Eduardo Romero, Marta Ibañez, Victor Manuel Lujan, Maria Elena López-Melero, Jorge Luis Martínez-Torrecuadrada, Francisca Mulero. Preclinical dosimetry of an 177Lu-labelled anti-MMP-14 antibody for triple-negative breast cancer (TNBC). Abstract 230. EMIM2024 (12-15/03/2024; Porto, Portugal)
  3. Aitor Herraiz, Juan Pellico, T.M. De Rosales, Eduardo Romero, Marta Oteo, Miguel Ángel Morcillo-Alonso, Fernando Herranz. Nano-radiopharmaceuticals for theranostics of cancer. 6th Spanish Conference on Biomedical Applications of Nanomaterials (SBAN); Madrid (28-29th September 2023).
  4. Iris Asensio, Begoña Gallardo, Carolina Franco, Christian Ruiz, Mario González, Miguel-Ángel Morcillo, Eduardo Romero, Javier Cubero, Gorka Sobrino, Marta Oteo, Manuel Desco, Rafael Bañares, Beatriz Salinas, Javier Vaquero. Molecular imaging for the non-invasive assessment of hepatic angiogenesis in rodent models of liver disease and regeneration. Jornadas colaborativas 2023 CIBEREHD y CIBER-BBN. Santander (España). 6-7 noviembre 2023.
  5. M.E. López-Melero, J. Praena, I. Porras, F. Arias de Saavedra, L. Fernández-Maza, A. Roldán, I. Da Silva, C. Ania, N. Magro, E. Romero, M.Á. Morcillo. Radioisotope production with deuterons for nuclear medicine at IFMIF-DONES. 21st International Conference on Fusion Reactor Materials" (ICFRM-21). Granada (España). 22-27 octubre 2023.
  6. Sara de Scals, Luis M. Fraile, Jose M. Udías, Marta Oteo, Miguel A. Morcillo, María N. Cabrera Martín, Samuel España. Development of a beta-probe based on scintillation fibers and silicon photomultipliers. 2023 IEEE Nuclear Science Symposium and Medical Imaging Conference; 4-11 November 2023. Vancouver (Canada).
  7. Sarasola Martin, J.I. Lagares, R. Méndez, R. Bedogni, L. Medina, J.M. Gómez-Ros, A.I. Castro Campoy, F. Sánchez-Doblado.  Uso de TLDs 600/tld700 y GR206/GR207 para dosimetría neutrónica a muy bajas dosis. 8º Congreso conjunto SEFM-SEPR . ISSN 2990-2916. Pág 1015-1016, 23-26 Mayo 2023.
  8. Arce Dubois, P.; Chamorro Claver, N.; Lagares Conzález, J. I.; Azcona Armendáriz, J. D.; Huesa Berral, C.; Fayós-Sola Capilla, R.; Viñals Muñoz, A. ; Villagrasa, C.; Perrot, Y.; Cirrone, G. A. P.; Petringa, G. Instalación de una herramienta de Monte Carlo  basada en GAMOS/Geant4 con cálculo del efecto biológico para la planificación de los tratamientos de protonterapia de la CUN. 8º Congreso conjunto SEFM-SEPR. ISSN 2990-2916. Pág 506-507, 23-26 Mayo 2023.
  9. Pedro Arce, Pedro Rato Mendes, Natalia Chamorro, Juan Ignacio Lagares, Oscar Vela, Jesús Marín, Borja Aguilar, Leticia Irazola, Juan Diego Azcona. A dedicated dual-head TOF-PET system for in-vivo quality control of beam delivery in proton therapy. PTCOG 61, 2023. Madrid. Spain.
  10. P. Arce, N. Chamorro, J. I. Lagares, N. Magro. J. D. Azcona, C. Huesa Berral, R. Fayos-Solá Capilla, A. Viñals Muñoz. C. Villagrasa, Y. Perrot, G.A.C. Cirrone, G. Petringa. Installation of a tool based on GAMOS/Geant4 with calculation of the biological effect for the planning of CUN proton therapy treatments. IGFAE workshop on technologies and applied research at the future Galician proton-therapy facility. 9-10 Mayo de 2023 (Santiago de Compostela).
  11. J.I. Lagares, M. Ibanez-Moragues, M. Oteo, M.Á. Martín, N. Chamorro, P. Arce, J.M. Pérez, M.Á. Morcillo. XR tube without monitoring chamber, dose corrections and implications in radiobiology results.  ESTRO 2023. Radiotherapy and Oncology, Volume 182, Supplement 1, Pages S1469-S1450, PO-1750, 2023.
  12. R. Bedogni, L. Russo, A. Fontanilla, A.I. Castro Campoy, A. Calamida, F. Sanchez Doblado, J.I. Lagares.  UCD: un dosímetro activo de lectura directa para radioterapia flash. 8º Congreso conjunto SEFM-SEPR. (Comunicación Oral). ISSN 2990-2916. Pág. 200-201, 23-26 Mayo 2023.
  13. J.I. Lagares, H. Miras, B. Sánchez-Nieto, I. Sarasola, R. Bedogni, M.A. Morcillo and F. Sánchez-Doblado. Dosimetry characterization of an electron flash equipment: energy dependence with pulse frecuency. Flash Radiotherapy and Particle Therapy. 5-7 December 2023. Toronto (Canadá).
  14. M. Ibáñez, N. Chamorro, J. I. Lagares, M.Oteo, V. M. Luján-Rodríguez, J. D. Azcona, M. A. Martin-Rey, E. I. De Almeida, P. Arce Dubois, J. M. Perez, M. Á. Morcillo. “Optimization of cell survival quantification method to study RBE with different LETs in a proton therapy irradiation facility”. 61st Annual PTCOG Conference, 10-16 June 2023, Madrid, Spain.
  15. N. Chamorro, M. Ibáñez, J. I. Lagares, M. A. Morcillo, J. D. Azcona, M. Oteo, B. Aguilar, J. M. Pérez, P. Arce. “Analysis and reduction of the uncertainty in clonogenic assays to allow modeling RBE as a function of LET.” 61st Annual PTCOG Conference, 10-16 June 2023, Madrid, Spain.
  16. L.M. Fraile, S. España, A. Espinosa-Rodríguez, V.V. Onecha, D. Sánchez-Parcerisa, M. García-Díez, P. Ibáñez, Víctor Martínez-Nouvilas, V. SánchezTembleque, J.M. Udías, C. Gutiérrez-Neira, S. Viñals, M.A. Morcillo, M. Ibáñez-Moragues, M.J.G. Borge, E. Nácher, P. Bragado, A. GutiérrezUzquiza, A. Porras, A. Mazal, J.A. Vera-Sánchez. “Contrast agents for in-vivo range verification in protontherapy”. 61st Annual PTCOG Conference, 10-16 June 2023, Madrid, Spain.
  17. P. Arce, P. Rato Mendes, N. Chamorro, J. I. Lagares, O. Vela, J. Marín, B. Aguilar, L. Irazola, J. D. Azcona. “A dual-head TOF-PET system for in-vivo quality control in proton therapy”. IGFAE workshop on technologies and applied research at the future Galician proton-therapy facility, 2023, Santiago de Compostela, Spain.
  18. P. Arce, N. Chamorro, J. I. Lagares, N. Magro, J. D. Azcona, C. Huesa Berral, R. Fayos-Solá Capilla, A. Viñals Muñoz, C. Villagrasa, Y. Perrot, G.A.C. Cirrone, G. Petringa. “Installation of a tool based on GAMOS/Geant4 with calculation of the biological effect for the planning of CUN proton therapy treatments”. IGFAE workshop on technologies and applied research at the future Galician proton-therapy facility, 2023, Santiago de Compostela, Spain.
  19. Ibáñez-Moragues, M; Chamorro, N.; Fernández-Barahona, I.; Oteo, M.; Lagares, J. I.; Arce, P.; Luján-Rodríguez, V. M.; Ramos-Martín, F.; España, S.; Fraile, L. M.; Azcona, D.; Morcillo, M. Á. “Radiobiology studies in proton therapy: range verification with Zn nanoparticles and studies of cell surveillance after irradiation with different LETs.” IGFAE workshop on technologies and applied research at the future Galician proton-therapy facility, 2023, Santiago de Compostela, Spain.
  20. Irene Castells-Yus; Ruth González-Gómez; Yago Margolles; Raquel Ibánez-Pérez; Noelia Mendoza Calvo; Eduardo Ruiz-López; Natalia Magro; Eduardo Romero; Juan Alberto Corbera; Roberto Pazo; Miguel Ángel Morcillo; Patricia Sancho; Luis Ángel Fernández; Alberto J. Schuhmacher. Generation of nanobody libraries for the development of immunoPET and fluorescence-guided surgery probes for pancreatic ductal adenocarcinoma. Mechanisms & Models of Cancer. 16-20 August 2022 (New York, USA)
  21. Mario González-Arjona; Lorena Cussó; John Jairo Aguilera-Correa; María Isabel González; Almudena Burillo; Silvia N. Vázquez; Patricia Muñoz; Eduardo Romero; Miguel Ángel Morcillo; Jaime Esteban; Manuel Desco; Beatriz Salinas. Detección in vivo de la infección por Staphylococcus aureus en un modelo de osteoartritis mediante inmunoPET. 9ª Jornada de Investigación e Innovación IiSGM. 8-9 junio 2022 (Madrid).
  22. P. Arce, N. Chamorro, J.I. Lagares, P. Rato Mendes, O. Vela, J. Marín, B. Aguilar, L. Irazola and J.D. Azcona. Monte Carlo simulation framework for the evaluation of PET detector designs in charged particle therapy applications. IEEE NSS MIC 2022.
  23. N. Chamorro, P. Arce, J.I. Lagares, M. Ibáñez, M.A. Morcillo, D. Azcona, M. Oteo, A. Viñals, J.M. Pérez. A comprehensive method to desing optimal cell irradiation with a scanning beam proton therapy machine considering LET dispersion. PTCOG 60, 2022. Miami Beach, USA.
  24. M. Ibáñez; I. Fernández-Barahona; R. Santacruz; M. Oteo; V. M. Luján; N. Magro; S. España; L. M. Fraile; F. Herranz; M. Á. Morcillo. “In vitro and in vivo evaluation of Zn nanoparticles for proton range verification in a glioblastoma cell line”. PTCOG 60, 2022, Miami Beach, USA.
  25. N. Chamorro, P. Arce, J.I. Lagares, M. Ibáñez, D. Azcona, M.Á. Morcillo, M. Oteo. On the need of using MC Simulations to optimize the design of a clonogenic assay to measure RBE as a function of LET and minimize the measurement uncertainty. IV Geant4 User Conference. Napoli, Italia, 2022
  26. Miguel Ángel Morcillo. ElectronFLASH en el CIEMAT, el primer equipo de investigación FLASH en España. Conferencia invitada al XXI Congreso SEOR. 28-30 septiembre de 2022 (Palma de Mallorca).