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Role of NF-κB in Ageing and Age-Related Diseases: Lessons from Genetically Modified Mouse Models
García-García, V.A.; Alameda, J.P.; Page, A.; Casanova, M.L.
Cells 2021, 10, 1906. https://doi.org/10.3390/cells10081906

CYLD Inhibits the Development of Skin Squamous Cell Tumors in Immunocompetent Mice.
Alameda JP, García-García VA, López S, Hernando A, Page A, Navarro M, Moreno-Maldonado R, Paramio JM, Ramírez Á, García-Fernández RA, Casanova ML.
International Journal of Molecular Sciences. 2021; 22(13):6736. https://doi.org/10.3390/ijms22136736

Functional Specificity of the Members of the Sos Family of Ras-GEF Activators: Novel Role of Sos2 in Control of Epidermal Stem Cell Homeostasis.
Baltanás FC, Mucientes-Valdivieso C, Lorenzo-Martín LF, Fernández-Parejo N, García-Navas R, Segrelles C, Calzada N, Fuentes-Mateos R, Paramio JM, Bustelo XR, Santos E.
Cancers (Basel). 2021 Apr 29;13(9):2152. doi: 10.3390/cancers13092152.
PMID: 33946974

A new non-aggregative splicing isoform of human Tau is decreased in Alzheimer’s disease. García-Escudero V, Ruiz-Gabarre D, Gargini R, Pérez M, García E, Cuadros R, Hernández IH, Cabrera JR, García-Escudero R, Lucas JJ, Hernández F, Ávila J.
Acta Neuropathol (2021). https://doi.org/10.1007/s00401-021-02317-z
PMID: 33934221

Generating New FANCA-Deficient HNSCC Cell Lines by Genomic Editing Recapitulates the Cellular Phenotypes of Fanconi Anemia.
Errazquin R, Sieiro E, Moreno P, Ramirez MJ, Lorz C, Peral J, Ortiz J, Casado JA, Roman-Rodriguez FJ, Hanenberg H, Río P, Surralles J, Segrelles C, Garcia-Escudero R.
Genes. 2021; 12(4):548. https://doi.org/10.3390/genes12040548

Huntington's disease-specific mis-splicing unveils key effector genes and altered splicing factors.
Elorza A, Márquez Y, Cabrera JR, Sánchez-Trincado JL, Santos-Galindo M, Hernández IH, Picó S, Díaz-Hernández JI, García-Escudero R, Irimia M, Lucas JJ.
Brain. 2021 Mar 16:awab087. doi: 10.1093/brain/awab087.
PMID: 33725094

Tackling tumor microenvironment through epigenetic tools to improve cancer immunotherapy
Lodewijk I, Nunes SP, Henrique R, Jerónimo C, Dueñas M, Paramio JM
Clinical Epigenetics volume 13, Article number: 63 (2021)
DOI: 10.1186/s13148-021-01046-0
PMID: 33802203

Cell Therapies in Bladder Cancer Management
Morales L, Paramio JM
Int J Mol Sci. 2021 Mar 10;22(6):2818.
DOI: 10.3390/ijms22062818
PMID: 33802203

XPO7 is a tumor suppressor regulating p21CIP1-dependent senescence.
Innes AJ, Sun B, Wagner V, Brookes S, McHugh D, Pombo J, Porreca RM, Dharmalingam G, Vernia S, Zuber J, Vannier JB, García-Escudero R, Gil J.
Genes Dev. 2021 Mar 1;35(5-6):379-391. doi: 10.1101/gad.343269.120. Epub 2021 Feb 18.
PMID: 33602872

Neuroendocrine Lung Cancer Mouse Models: An Overview
Lorz C, Oteo M, Santos M.
Cancers 2021, 13, 14
PMID: 33375066
doi.org/10.3390/cancers13010014